Spironolactone tablets and furosemide tablets can be taken together for edematous diseases, hypertension and primary aldosteronism, etc. The dosage and the time of administration vary for different diseases. 1. Edematous diseases: for example, renal edema, hepatic edema, etc., such as the use of spironolactone plus furosemide, you can choose to take 40-120 mg of spironolactone tablets per day, 2-4 times a day; furosemide dosage of 20-40 mg, once a day. 2. Hypertension: patients with hypertension can choose to take 40~80mg of spironolactone tablets per day, and the dose of furosemide is 40~80mg, which can be divided into two times. 3. primary aldosteronism: if surgery is needed, the dosage of spironolactone tablets before surgery is 100~400mg, while furosemide can be taken 80~120mg before surgery, which can effectively prevent hypercalcemia. Take spironolactone note, such as drug allergy to any of the components, need to be prohibited, hypokalemia and the use of digitalis patients prohibited, if there is azotemia, anuria, prohibited. For myocardial infarction and diabetic patients need to be used with caution. Long-term use of this product may occur gastrointestinal discomfort, allergic reactions, etc., will be relieved after discontinuation of use. Furosemide is contraindicated in people who are allergic to the components of the product, and should be used with caution in children, during pregnancy and breastfeeding. Prolonged use of this product may cause electrolyte disorders, inducing hypokalemia, which can be relieved after discontinuation of the drug and does not require special treatment. If there is any adverse reaction during the use of the drug, it should be discontinued under the guidance of a professional physician, and the specific use of the drug should be carried out under the guidance of a physician.