Gallstone surgery is currently minimally invasive and relatively minor. However, if bile duct stones are ineffective with minimally invasive treatment, open surgery is required and is considered major surgery. Gallstones refer to the formation of stones in the gallbladder or bile ducts. Most patients are asymptomatic, while some may experience symptoms such as colic in the upper right abdomen. For those with obvious symptoms, a large number of stones and a large diameter of stones, or when accompanied by gallbladder polyps, early surgical treatment is required. For patients with gallbladder stones, minimally invasive laparoscopic cholecystectomy is currently the mainstay of minor surgery. For patients with bile duct stones, endoscopic retrograde pancreaticobiliary lithotripsy is preferred, which is also minor surgery. However, if the stone can not be completely removed during the operation, it is necessary to leave the nasobiliary drainage, the biliary obstruction will be lifted, and then choose the choledochotomy, stone extraction, often also need to use choledochoscopy and placement of the “T” shaped tube, the operation is more complex, it is a major surgery. If you suffer from gallstones, it is recommended that you go to a regular hospital and cooperate with your doctor to choose the right treatment. Daily need to maintain a good mood, avoid too nervous. After surgery, patients should pay attention to diet, avoid overeating, develop good habits and drink more water.