At present, the new drugs for ankylosing spondylitis are anti-tumor necrosis factor antagonist drugs, which can block the inflammatory response in the body, effectively reducing symptoms and alleviating the condition. Anti-tumor necrosis factor antagonists can only play a palliative role, and can not carry out radical treatment, commonly used biological agents anti-tumor necrosis factor antagonists, such as recombinant human type II tumor necrosis factor receptor antibody fusion protein, etc., you need to choose the right drug under the guidance of a doctor! It should be noted that before applying biological agents, tuberculosis infection as well as hepatitis B virus infection must be excluded first. At the same time, the use of such drugs may cause skin itching, hives, fever, etc. If the symptoms are serious, you should consult a doctor in time. In addition, the treatment cost of biologics is relatively high, so few people can use them for a long time, so most people can gradually reduce the dosage of biologics after 3-6 months of full dosage, and then switch to oral anti-rheumatic drugs for maintenance treatment. All medications should be used as prescribed.