Platelet 61×10^9/L is lower than the normal value, and it is considered to be related to the related diseases such as decreased platelet production, excessive platelet consumption or destruction. 1. Reduced platelet production: hematologic diseases such as aplastic anemia and leukemia, certain drugs (hydroxyurea), radiotherapy (cytarabine), tumors, etc. can affect the hematopoietic function of bone marrow or damage the hematopoietic stem cells, which can lead to reduced platelet production. 2. Platelet destruction and excessive consumption: common in primary immune thrombocytopenia, disseminated intravascular coagulation, certain infections and hypersplenism. When platelets are lowered, it is recommended to consult a doctor in time to clarify the cause of the disease and standardize the treatment under the doctor’s guidance.