Prostate cancer to the end, clinically that is to say advanced stage, this is when pain symptoms can appear. Generally, most of the cancers in the advanced stage will have pain symptoms, mainly due to the fact that the cancer grows to a certain extent, which will destroy the surrounding tissues, and may also compress the nerves, bones and so on to cause pain. When prostate cancer reaches the advanced stage, metastasis may also occur, and bone metastasis mostly occurs in the whole body, which will lead to persistent bone pain, especially when the patient lies down, the pain symptom will be more obvious, and if the condition is serious, it may also lead to pathologic fracture phenomenon. This kind of cancer pain is usually unbearable for patients, and strong painkillers such as oxycodone and morphine can be used under the guidance of doctors to relieve pain. It is suggested that if patients are diagnosed with prostate adenocarcinoma, they should go to the hospital for treatment in time. Doctors will formulate appropriate treatment plans according to the specific conditions of the patients in order to alleviate their pain and improve the quality of their survival.