Drinking alcohol after eating durian is not recommended because it is rich in vitamins and histamine, a substance that can aggravate allergic reactions. For example, if you have a previous allergy to durian or an allergy to alcohol, drinking alcohol after eating durian will increase the probability of allergic reactions and cause allergic rashes, rashes, papules, hives, and red, itchy skin. It can also lead to an increased reaction to alcohol allergy and alcoholism, which can cause nausea, vomiting, acid reflux, heartburn, abdominal pain, diarrhea, and other conditions. Durian can cause cold stimulation of the gastrointestinal tract, and alcohol can also cause some mucosal erosion and damage to the gastrointestinal tract. Therefore, drinking alcohol after eating durian can increase the load on the gastrointestinal tract, leading to abdominal pain and even diarrhea.