Drinking beer after eating durian is usually not recommended, because there is a component in durian that weakens the activity of acetaldehyde dehydrogenase in a large amount, and drinking beer after eating durian will cause a large amount of acetaldehyde in alcohol to accumulate in the liver, which will not be metabolized out of the body immediately and will produce alcohol poisoning. Severe alcohol poisoning can cause toxic shock, which can be life-threatening. The reason why you should not drink beer after eating durian is because the bacteriocins in durian can increase the permeability of alcohol and cause damage to the gastric mucosa, leading to upper gastrointestinal bleeding and vomiting of blood. In some cases of diabetes and cardiovascular disease, such as previous myocardial infarction and cerebral infarction, drinking beer after eating durian can increase the risk of cerebrovascular blockage and, in severe cases, acute stroke.