The more important treatment for skull base destruction is causative treatment. The cause of skull base destruction must be promptly identified, including the gradual erosion of tumors and the gradual compression of vascular disease, which may cause the destruction of skull base bone, and even in the case of trauma may also cause skull base fracture, causing the destruction of skull base bone, requiring surgery to remove tumors or cerebrovascular disease, as well as the corresponding skull base reconstruction and repair, in order to more effectively treat the skull base The femoral bone destruction can be treated more effectively. Especially for malignant tumors, not only surgical resection but also surgical repair of skull base is needed, and even radiation therapy and chemotherapy are needed at a later stage to solve the problem of skull base tumors together, so there are many ways to treat skull base bone destruction, and it is important to distinguish the specific types and treat them early to minimize the degree of skull base destruction.