The bone destruction of the skull base seen in clinical practice means that the corresponding bones of the skull base are damaged by certain factors, such as fractures of the skull base caused by trauma, or factors of tumor and vascular disease, which constantly grows and affects the relevant bones of the skull base, causing the destruction of the bones of the skull base. The skull base is protected by a dense layer of bone, such as the anterior skull base, middle skull fossa base, and posterior skull fossa base. Any tumor, trauma, or vascular disease constantly attacking the skull base bone will cause cerebrospinal fluid leakage, as well as swelling, pain, and a series of other conditions, which will show the destruction of the skull base bone in clinical imaging. It is difficult to treat at all.