Oral white spots are white patches on the oral mucosa that cannot be clinically or pathologically diagnosed as other diseases, and their etiology is not yet well understood, but may be closely related to smoking, local irritation and Candida infection. Most of the white spots usually have no other discomfort symptoms except for the local feeling of coarseness, and if erosion occurs, there can be pain. At this stage, there is no special treatment for oral leukoplakia. First of all, all possible stimulating factors should be removed, such as grinding and changing sharp edges and tips, modifying dentures with rough and sharp edges, extracting residual roots and crowns, especially quitting smoking and abstaining from drinking alcohol. Patients who are diagnosed with leukoplakia should be treated under the guidance of a doctor, and medication or surgery can be used according to the situation. For white spots with granular, warty or erosive ulcers and white spots occurring on the edge of the tongue, the floor of the mouth – tongue belly, and the soft palate complex area of the mucosa in the corner of the mouth, those who do not have good results with conservative treatment should be surgically removed as early as possible and pathological biopsy should be performed, because white spots of these types and parts are prone to cancer. Patients with oral leukoplakia and those who have been cured still need to be reviewed every six months to one year to prevent recurrence and facilitate timely treatment. As oral leukoplakia is a precancerous lesion, highly targeted and effective preventive measures should be taken. For middle-aged people and above, the system of regular oral health checkups should be implemented carefully and attention should be paid to the follow-up observation.