Although titanium mesh is a commonly used cranial repair material in clinical practice, the current situation does not recommend the use of titanium mesh. Cranial bone repair materials are constantly developing and progressing, titanium mesh material is much more advanced than other materials in the past, but there are still some problems and shortcomings, not very ideal, and clinical use of this and that kind of problem from time to time. For example, some patients ask what is the status of titanium mesh exposed after cranial repair. Titanium mesh material repair of the skull after the material exposure is indeed a big problem, which is mainly due to three reasons: one part may be related to the rejection of the material, titanium mesh material, although the histocompatibility has been good, generally will not be rejection phenomenon, but clinically there may still be some patients on the titanium mesh material of the immune response is more sensitive to the rejection of the situation, which would cause the scalp tissue ablation breakthroughs, the material exposure; the other part may be due to the postoperative period of titanium mesh material, the material exposed; another part may be due to the postoperative period of titanium mesh material, the material is not very satisfactory. Another part may be due to postoperative wound infection, resulting in poor skin healing, there will also be tissue breakage material exposure; Another part may be due to the titanium mesh material on the scalp to produce abrasion or cutting damage, because the titanium mesh is a covered repair, the material edge is relatively sharp, and even more sometimes the titanium mesh material may be deformed, the edge of the warped, which will cause damage to the skin, ultimately resulting in the titanium mesh exposed; Of course, there are also some patients who may be sensitive to the immune response of the titanium mesh material, resulting in ablation of the scalp tissue breakage, material exposure. Of course, there may be other reasons as well. Exposed titanium mesh is very dangerous, will further increase the risk of infection or even cause intracranial infection, also vulnerable to external aggression, injury to the brain tissue, affecting nerve function, and also has a great impact on the appearance of the patient’s psychological burden, so it should be dealt with as soon as possible, and if necessary, need to take out the titanium mesh, and then re-do the cranial repair after the skin grows well. When repairing again, it is recommended to use the new polyether ether ketone PEEK material, this new material has excellent performance, comparable to the autologous skull, which has become the new trend of cranial bone repair materials, and has been gradually popularized and popularized in various parts of the world.