Due to the tumor itself, surgery, radiotherapy, etc., patients are mostly in an immunocompromised state and belong to the susceptible group of neococcal pneumonia. Tumor patients during the epidemic should need to pay more attention to protection than ordinary people to eliminate the possibility of infection. For patients with initial diagnosis, it is recommended that they come to Beijing with negative nucleic acid test results within three days after completing the examination in local hospitals; or consult with our experts through teleconsultation to clarify the follow-up treatment plan. We will decide on the itinerary according to the hospital’s treatment arrangement. Patients with clear diagnosis waiting for surgery: Most of the patients with brain tumors have slow progression of the disease, and after it is clear that they need to be admitted to the hospital for treatment, they should undergo the nucleic acid test in time, and arrange for admission to the hospital for treatment after the negative result is clear. During the waiting period, patients need to pay close attention to their own situation, keep in touch with the supervising physician, and arrange treatment according to the specific situation after the epidemic is over. Patients with tumor combined with serious complications requiring emergency treatment: Patients with progressive deterioration of state of consciousness, persistent epileptic state, fever, severe vomiting, etc. should immediately seek emergency treatment at local hospitals. Enhanced nursing care and reduced visitation are required to ensure the safety of the patient during the perioperative period. Post-operative patients: Post-operative patients who have completed surgery and are still in the hospital for treatment should pay attention to self-protection and actively cooperate with the treatment. Patients who have been discharged from the hospital should be strictly isolated and recuperate at home, avoid going out and gathering activities, exercise appropriately and enhance nutrition. For patients who need adjuvant radiotherapy, contact the radiotherapy department for timely nucleic acid test, and carry out the treatment according to the arrangement after the result is clear and negative. Patients during radiotherapy: For tumor patients with normal physical condition, they can continue to receive treatment in an orderly manner according to the overall arrangement of the local hospital, paying attention to the testing of blood routine and immune function. For old and immunocompromised patients, they should be strictly protected during consultation; or the chemotherapy cycle should be extended appropriately without affecting the tumor treatment and prognosis. Both radiotherapy and chemotherapy may lead to decreased immunity, which is not conducive to the prevention of neocoronitis. Postoperative follow-up and review patients: Routine review patients are appropriately delayed to the maximum interval required by the guideline, and strict protection is required at the time of visit, the overall efficacy of the treatment will not be fundamentally altered by the absence of 1-2 follow-up visits, and it is recommended to review patients close to their home, and to reduce the length of stay in the hospital through teleconsultation. Common emergency condition changes Seizures: Seizures can not be forced to press the patient’s limbs, try to let the patient lie down naturally, if there is vomiting, pay attention to turn the patient’s head to the side in a timely manner, at the same time, take out the foreign objects in the mouth, remove vomitus in a timely manner in order to prevent accidental inhalation, such as the first time a seizure, should be timely access to medical treatment to identify the cause of the seizure and symptomatic treatment, such as the past have had a seizure, should be excluded from the epilepsy triggering factors, standardize the use of If there are previous seizures, exclude seizure triggering factors, standardize the use of antiepileptic drugs, and adjust the dosage of drugs if necessary. Fever: It is mainly seen in patients discharged from the hospital after surgery. When the body temperature exceeds 38℃, and extracranial factors such as cold and flu are excluded, fever related to brain tumor surgery should be considered: incision infection, cerebrospinal fluid leakage with intracranial infection, retrograde infection of drainage tubes, prolonged bed-ridden (indwelling urinary catheter, postoperative pulmonary or urinary tract infection), and fever should be treated in the clinic and contacted with the surgeon. Headache: Preoperative headache is not improved by mannitol infusion and is accompanied by vomiting and blurred consciousness requiring immediate medical attention. Short-term postoperative headache, vomiting, mostly due to cerebral edema, the former infusion of mannitol, dexamethasone after improvement. After discharge from the hospital, headache with fever again, need to consult the doctor, exclude the new coronary pneumonia virus infection, and then consider intracranial infection.