Clinically, breast nodule 4C is considered to have a higher possibility of malignancy, and the probability of malignancy is >50% and ≤95. Surgical treatment is usually recommended, with mastectomy of the breast mass first, and the need for further surgery is decided according to the intraoperative rapid frozen pathology results. If the pathological result is malignant, radical mastectomy should be performed, and postoperative adjuvant chemotherapy should be performed if invasive breast cancer with axillary lymph node metastasis is clearly identified, and commonly used chemotherapeutic agents are epirubicin, cyclophosphamide, docetaxel, etc. If the pathologic result is benign, the incision can be sutured and the operation can be concluded. Breast nodule 4C has a high malignant potential, early surgery to clarify the diagnosis can still harvest a better prognosis, it is recommended to actively treat the disease to avoid the progression of the disease, leading to adverse consequences.