Pimples around the mouth in women usually belong to a skin condition called acne, which is generally not related to gynecological disorders. The medical term for acne is acne vulgaris, which is related to imbalance of hormone levels in the body, high sebum production, keratinization of the hair follicle opening, and Acinetobacter infection. Women often have acne around the mouth, usually due to excessive use of skin care products around the mouth, resulting in high oil secretion and blockage of hair follicle buckles, which causes inflammation. In addition, pre-menstrual period, adolescent women, or after eating too much spicy and stimulating, fatty and greasy food, will also appear around the mouth acne phenomenon. Patients should pay attention to the regulation of daily life, light diet, appropriate increase of vegetables, fruits and other vitamin-rich food, avoid spicy, cold, greasy food. In addition, patients need to keep their skin clean, use appropriate skin care products, and avoid squeezing when acne occurs. If necessary, visit a hospital dermatologist and give oral and topical medication.