HFMD is a common acute childhood infectious disease, which belongs to the gastrointestinal tract and is mainly caused by intestinal viral infections and is common in children under five years of age. The source of HFMD infection is mainly the affected child and the latent infected person, and the affected child is better distinguished, that is, the child who has HFMD. This type of child is infectious from 3-5 days before the onset of the disease until two weeks after the disease. There is also a type of recessive infectious person, which mainly includes the parents of the affected child or other children who have been in contact with the affected child. These children or parents are exposed to the HFMD virus and do not develop the disease themselves, but can infect other children through hand contact. To fundamentally prevent HFMD, we must pay attention to personal hygiene, pay attention to the disease from the mouth, and improve our own immunity.