To understand this aspect of the outpatient process of HFMD, it is necessary to first understand the extent of the outpatient rash. It usually appears in the area of the throat, the isthmus, where pharyngitis occurs. Also, it is more obvious that it appears on the palms of the hands, feet, and skin around the anus. If the rash expands, it can appear on the backs of the hands and feet as well as the buttocks. Further obvious ones can appear on the trunk, and there are some extremities where the rash can appear near the large joints, like the knee, shoulder, and elbow joints. Patients with especially large rashes may have a rash all over the body, but the rash on the hands, feet, and buttocks should not be missing either. For the timing of the appearance of these rashes, herpetic pharyngitis appears first, and a red papule or ruptured herpes can appear at the back of the soft palate, which is followed by a sore throat. After that, the rash can appear first around the anus, sometimes earlier than the appearance of herpes on the palms of the hands, sometimes in parallel with the appearance of herpes on the hands, and sometimes on the hands and feet in just one area, such as appearing on the hands or appearing on the feet. For the more typical cases, the rash can appear on both hands and feet, and then the rash can appear on the trunk, large joints of the limbs, or even all over the skin. This is the general process of the appearance of the rash of HFMD.