According to the degree of pathological deterioration, invasive ductal carcinoma of the breast can be classified into grade I, grade II and grade III. Grade I is less malignant, grade II is intermediate differentiation and moderate malignancy, and grade III is low differentiation and higher malignancy. For the treatment of grade II invasive ductal carcinoma of breast, there are two main clinical categories: surgical treatment and conservative treatment. For grade II patients without metastasis, surgical resection can be used for radical treatment, and post-operative treatment with radiotherapy and chemotherapy can help recovery, and regular blood tests, abdominal CT and liver function can be actively performed to observe the metastasis of cancer cells in time. For patients with metastasis, conservative treatment is generally recommended, and non-surgical treatments such as chemotherapy, endocrine therapy or targeted therapy are recommended to delay the disease, reduce patients’ pain and improve their quality of life.