What is invasive ductal carcinoma of the breast?

Invasive ductal carcinoma of the breast, also known as non-specific type of carcinoma, is a group of heterogeneous invasive carcinomas that do not achieve sufficient characteristics to be classified as a specific tissue type and is the most common type of invasive breast cancer, accounting for 40%-70% of cases. Clinically palpable lumps in the breast are irregular in shape, hard and tough, and often fixed to varying degrees to surrounding tissues, such as deep muscular layers or surface skin. It is irregular or nodular in general appearance, often concave in section, with visible yellowish-white streaks and may feel gritty. Under the microscope, there are different structural arrangements, in the form of cords, beams, masses, glandular ducts, solid, lamellar, etc. There are different cell morphology, the cells are often relatively large, in different shapes, adhesive, often with abundant eosinophilic cytoplasm, with different nuclear levels, the nucleus ranges from regular to with obvious polymorphism, the nucleolus is often obvious, there may be multiple nucleoli, there are different interstitial components, including myofibroblasts, collagen fibers, the There are different interstitial components, including myofibroblasts, collagen fibers, elastic fibers, etc. There are different infiltration patterns and degrees, including infiltration of fat, muscle tissue, involvement of vascular nerves, etc., and there are often components of high-grade intraductal carcinoma. Its prognosis is generally related to tissue stage, tumor volume, lymph node metastasis, vascular infiltration, and ER and HER2 status. Therefore, it is recommended that patients must have regular health checkups for early detection and early treatment to avoid delaying the disease.