Upset, all have a reason. In life, all unhappy things can be expressed as upset. You can be criticized by your leader, quarrel with your wife, can’t afford a car or house, etc. If you are always upset, especially for no reason, you should think about the possibility of getting sick. If you are always upset, especially if you are upset for no reason, we should think about the possibility of getting sick. Because there is a type of upset is related to disease. According to Chinese medicine, most of the heartburn belongs to heat evidence. In the “Treatise on Typhoid Fever”, all six meridians can manifest as annoyance. Clinically, the residual evil after a cold can have heart trouble, a cold with high fever can have heart trouble, and a chronic disease in internal medicine can also have heart trouble. Modern medicine also has a lot of recognition that menopausal syndrome, anxiety and depressive states, and menstrual irregularities may be related. According to Chinese medicine, “the heart is the official of the sovereign”, the most important of the five internal organs, the heart’s long-term, stable work is a key factor in our health and longevity, and diseases related to the heart can affect the state of the whole body and significantly reduce our quality of life. So there are symptoms of concern, panic, chest tightness, unexplained heartburn, we should pay attention to, and early medical treatment is necessary.