The normal value of alpha-fetoprotein should be less than 25μg/L. A significantly elevated alpha-fetoprotein of 144μg/L may be related to liver diseases, tumors, etc., which need to be examined and treated after the cause is clarified. Elevated alpha-fetoprotein may be related to hepatitis, cirrhosis of the liver, primary liver cancer and ovarian cancer and other tumor diseases, and it is necessary to actively find out the cause of the disease and treat according to the cause. 1. Hepatitis and cirrhosis: when patients with hepatitis and cirrhosis have liver function damage and transaminases are obviously abnormal, due to the self-repairing function of the liver, alpha-fetoprotein can be elevated to different degrees during the process of repairing, which is mainly caused by the regeneration of liver cells. Generally, alpha-fetoprotein is often less than 300μg/L, and with the improvement of liver function, alpha-fetoprotein will gradually decline. 2. Primary hepatocellular carcinoma and ovarian cancer: when liver cells or embryonic tissues of gonads undergo malignant changes, cells with the ability to synthesize alpha-fetoprotein are activated again, so that the synthesis of alpha-fetoprotein increases, resulting in a significant elevation of alpha-fetoprotein in the blood, and the value of alpha-fetoprotein of the majority of the patients is often greater than 300 μg/L, which is of great value in the diagnosis of hepatocellular carcinoma and ovarian cancer. 3. Other tumors: elevated alpha-fetoprotein is of great value in the diagnosis of testicular cancer, malignant teratoma and other tumors; alpha-fetoprotein can also be mildly elevated in malignant tumors such as lung cancer, gastric cancer and colorectal cancer. Elevated alpha-fetoprotein is related to many diseases and needs to be analyzed comprehensively with clinical symptoms, medical history and imaging results. Patients with elevated alpha-fetoprotein should go to the hospital in time, improve the relevant examinations with the help of doctors to clarify the cause of the disease, and give appropriate symptomatic treatment to avoid delaying the condition and the time of treatment.