The major and minor triplets are different situations after infection with the hepatitis B virus, but both are contagious which is no doubt, the major triplets have more obvious viral replication and are more contagious, while the minor triplets have relatively less viral replication and are less contagious. But whether it is major triplet or minor triplet, they are all contagious and need to be prevented, certainly not as a blood donor, not to donate blood. Be very careful in daily life especially with blood exposure, such as the patient used nail clippers, shavers and other beauty appliances, etc., may be contaminated, regardless of the major triplet and minor triplet, it is possible to contaminate later with the virus, it may be infectious, pay special attention to close living contact, there are also couples between the virus can also be transmitted through sexual life. So regardless of the big three yang, small three yang, the prevention or prevention, no vaccine should be vaccinated, but also depends on the amount of antibodies enough, not played it is okay, played to see the amount of antibodies enough, not enough also need to replant. If the amount of antibodies is not enough after the vaccination, it is not enough to protect the patient, so it is necessary to further strengthen the treatment and vaccination to produce sufficient amount of antibodies. The main way of transmission is through blood, close contact and sexual transmission, but the degree of transmission varies.