The typical symptom of poor coagulation is bleeding. The most common are nosebleeds or the appearance of purpura, or subcutaneous bleeding, in the skin, such as bruises and petechiae. Early on, scattered bleeding spots on the skin are visible, with no clear trend of distribution; the bleeding spots appear randomly. In severe cases, the bleeding spots may join together in patches, resulting in large areas of purpura on the skin, which is usually associated with long-term use of anticoagulant drugs. There is also a portion of the population associated with blood disorders. In addition, bleeding gums are a common symptom, especially after brushing teeth, and are associated with coagulation insufficiency. There may also be hematuria, or gastrointestinal bleeding, which is bloody stools, and in some patients, bleeding from joint cavities, similar to hemophilia.