There is no clinical advice not to recommend 60 micrograms of Hepatitis B vaccine, sometimes 60 micrograms of Hepatitis B vaccine is used in catch-up vaccinations, and it is recommended to choose the vaccine under the guidance of your doctor. Hepatitis B vaccine is an inactivated virus that can prevent Hepatitis B. Common sizes include 10 mcg, 20 mcg, and 60 mcg. A single dose of 60 micrograms of hepatitis B vaccine is relatively large and produces higher titers of protection. If the initial 20 mcg vaccination does not produce the appropriate amount of antibodies, the 60 mcg hepatitis B vaccine can be supplemented with the 60 mcg vaccine to increase the amount of antibodies produced in the body on the advice of a doctor. There is no clinical reason not to recommend 60 micrograms of Hepatitis B vaccine, and it is recommended that you choose the appropriate vaccine based on your symptoms under the guidance of your doctor.