Urine protein qualitative +- means that this qualitative is between negative and positive, which is usually referred to as weak positive, or means half plus. This condition can be seen in cases of physiological heavy physical activity, exertion, staying up late, and prolonged standing. It can also be seen in tonsillitis, pharyngitis or gastroenteritis and other related diseases. In addition, the most common diseases are chronic nephritis and nephrotic syndrome and secondary nephropathies, such as diabetic nephropathy, lupus nephritis, and myeloma nephropathy. In addition to these factors, urinary tract infections, urinary stones or tuberculosis, and sometimes malignant tumors of the renal pelvis or ureter can also show a qualitative plus or minus sign of urine protein, and in addition to this test result, sometimes the test for urine occult blood can be combined with a positive result.