Patients with chronic renal failure uremia need hemodialysis three times a week to maintain life, with the aim of removing excess water and toxins from the muscle and maintaining stable water-electrolyte and acid-base balance. If patients do not control their weight during the interval of dialysis, it will lead to a lot of weight gain, resulting in too fast and too much ultrafiltration during dialysis. Patients will show symptoms of hypotension, which manifests as dizziness, nausea, muscle cramps, individual patients will have profuse sweating, cold extremities, systolic blood pressure drop, >20mmHg, and mean arterial pressure drop by 10mmHg, which will lead to loss of consciousness in a long time. It is necessary to stop dialysis as soon as possible, keep the patient’s head in a low position, and infuse saline or glucose intravenously to achieve improvement.