If there is severe pain in one side of the throat and you cannot eat down. If the pain is recurrent and may be accompanied by pain at the base of the tongue or by pain in the external ear canal, you should be alert to the possibility of glossopharyngeal neuralgia. Glossopharyngeal neuralgia is a recurrent paroxysmal pain that occurs in the deep part of the tongue and ears. Weisenburg first reported the clinical manifestations of this disease in 1910, and in 1921 Harris proposed that glossopharyngeal neuralgia was a separate cranial neuralgia. The incidence is about 2% of that of trigeminal neuralgia. The disease usually occurs after the age of 40, and there is no significant difference in the incidence between men and women. Left-sided pain is more common than right-sided, and bilateral pain is present in about 2% of cases. The pathogenesis of this type of pain is similar to that of primary trigeminal neuralgia, which is due to vascular compression, resulting in demyelination of the linguopharyngeal and vagus nerve filaments at the point of compression, causing a “short circuit” between the nerve fibers and triggering the pain attack. Secondary linguopharyngeal neuralgia: It can be secondary to various tumors around the linguopharyngeal nerve, vertebral arteriosclerosis, aneurysm, residual inferior lingual artery, arachnoiditis, local infection, excessive stem length, ossification of the ligament of the stem ligament, injury to the extracranial segment of the linguopharyngeal nerve, occlusion of the extracranial end of the internal carotid artery and stenosis of the external carotid artery, resulting in ischemic changes in the linguopharyngeal nerve near the jugular foramen and formation of pseudo-synapses. The main drug treatment is carbamazepine, but microvascular decompression of the linguopharyngeal nerve is required for radical treatment.