Perianal inflammation is an inflammatory disease that occurs in the perianal skin. To get a radical cure for perianal inflammation, patients can improve their condition through general treatment, medication and surgery. 1. General treatment: patients should pay attention to keep the perianal local skin clean and dry, you can use saline soaked soft towel to wash the perianal skin, reduce the stimulation of pollutants on the local broken skin. Patients should avoid scratching the skin, bathing to avoid high water temperature, should also pay attention to a light diet, eat more fiber-rich fruits and vegetables, to maintain smooth bowel movements, avoid eating spicy and irritating foods, avoid alcohol and tobacco. 2. Medications: patients can use topical medications under the guidance of a doctor, such as zinc oxide ointment, glycerine lotion, boric acid solution, etc.; antibiotic ointment, such as erythromycin ointment, mupirocin ointment, etc., for local treatment, when the affected area of the itching, pain, and other symptoms of the patient can be injected with subcutaneous lidocaine to alleviate the symptoms. 3. Surgery: If the perianal inflammation patients with fistula, perianal abscess, etc., need to be operated by a professional doctor for surgical treatment, such as fistula incision, incision and drainage surgery. It is recommended that patients strictly follow the doctor’s instructions for medication, actively cooperate with the doctor’s treatment, pay attention to monitoring the condition in life, if there is any abnormality timely medical treatment.