There is no such thing as the fastest cure for acute cholecystitis, and the treatment should be targeted according to the specific condition. Acute cholecystitis can be categorized into acute calculous cholecystitis and acute non-calculous cholecystitis, which should be intervened by general treatment, amoxicillin, atropine and other medications, and surgical treatment. 1. Acute stone cholecystitis: (1) General treatment: fasting, rehydration, correction of water and electrolyte disorders; strengthen rest, avoid strenuous activities. (2) Drug treatment: for the symptoms of biliary colic, atropine, acetaminophen and other drugs can be applied under the guidance of doctors for treatment. (3) Surgical treatment: once diagnosed as acute calculous cholecystitis, cholecystectomy should be performed in time. 2. Acute non-stone cholecystitis: (1) General treatment: during the acute period, fasting and fluid replacement should be done, rest should be strengthened, and changes in the condition should be closely observed. (2) drug treatment: for bacterial and fungal infections caused by this disease, can be treated with amoxicillin, fluconazole and other drugs under the guidance of the doctor. If the pain symptoms are obvious, it can also be treated with scopolamine and other drugs. (3) Surgical treatment: according to the patient’s condition, cholecystostomy, partial cholecystectomy and other ways of treatment can be taken under the guidance of the doctor. The patient’s condition is different, the specific medical measures, must be in the medical doctor to confirm the diagnosis, follow the doctor’s guidance.