High uric acid and proteinuria are considered to be the possibility of gouty nephropathy, and the treatment includes general treatment and medication. General treatment: Dietary intake of animal offal, high sugar drinks, alcohol, seafood and desserts should be avoided, and more vegetables and water should be consumed. Maintain weight control and a healthy lifestyle. Drug therapy: Drug therapy mainly focuses on lowering uric acid, such as allopurinol, febuxostat, benzbromarone, etc.; at the same time, attention should be paid to controlling blood lipids and alkalizing urine. Colchicine and hormonal drugs such as prednisone can be used in acute attacks of gout. It is recommended that patients with high uric acid and proteinuria should go to regular hospitals for timely consultation and examination, choose the appropriate treatment according to the cause of the disease, and avoid self-medication, so as not to cause adverse effects and delay the condition.