Clindamycin phosphate gel can not be used all the time, all the time may produce drug resistance, as well as cause local irritation, rash and other adverse reactions. Clindamycin phosphate gel is an anti-acne drug, has a good antibacterial effect on Propionibacterium acnes, but also can make the skin surface of the fatty acid reduction, which is conducive to the treatment of acne. Clinically, it is mainly used for the treatment of common acne. Clindamycin phosphate gel can not be used for a long time, because even the safest drug used for a long time will easily cause the body to develop drug resistance, so that the effect of the drug is greatly reduced. At the same time, long-term use may cause dry skin, local irritation, rash, occasional gastrointestinal discomfort and diarrhea and other adverse reactions. Clindamycin phosphate gel is contraindicated for those who are allergic to the product and its components; those with a history of enteritis or ulcerative colitis. If you need to use the drug, should be used under the guidance of a doctor, do not use on their own to avoid adverse effects.