Children with large flat bumps on the body is very itchy, may be urticaria, urticarial vasculitis caused. It is recommended to clarify the cause, for the cause of the symptomatic oral, with topical drug treatment. 1. Urticaria: food, various viral infections, drugs, can cause allergic reactions, resulting in large flat bumps on the skin, itchy. Antihistamines such as loratadine, ebastine and olopatadine hydrochloride can be given in combination with the doctor’s advice. Antihistamines alone, the symptoms can not be relieved, can be given cimetidine, famotidine and other H2 receptor antagonists. Oral glucocorticoid drugs such as prednisone can also be given to control inflammation and angioedema. 2. Urticaria vasculitis: the cause of most urticarial vasculitis is not clear, and it is considered to be related to drugs, infection, autoimmune disease and other factors. Hormone cream can be given symptomatically, oral loratadine, ketotifen can reduce itching. Glucocorticoid drugs, such as prednisone acetate, can reduce the skin inflammatory reaction, reduce vascular inflammation. Suggestions, light diet during treatment, do not eat spicy stimulation, seafood food, do not often scratch with your hands to avoid aggravation of the condition.