There are many reasons for numbness in the palms of the hands, and the pathological causes may be caused by cervical spondylosis, carpal tunnel syndrome and peripheral neuritis. 1. Cervical spondylosis: some degenerative lesions of the cervical spine can compress the nerve roots of the upper limbs, resulting in numbness and weakness of the nerves of the upper limbs. In addition to numbness in the palm, there can be numbness in other parts of the upper limbs, as well as pain in the cervical spine and restricted movement. 2. Carpal tunnel syndrome: It is a peripheral nerve compression syndrome caused by the compression of the median nerve in the carpal tunnel. The main symptoms are pain in the anterior part of the wrist and numbness and weakness of the hand, which are commonly found in the area of thumb, finger and middle finger where the median nerve is distributed. 3. Peripheral neuritis: Peripheral neuritis is caused by poisoning, infection, allergy and other factors. Common symptoms include numbness of the distal limb on the opposite side of the limb, glove-like pain, and decreased motor muscle strength. There are many other causes of numbness in the palm of the hand, and it is recommended that patients consult the cause of the disease in a timely manner, according to the specific guidance for treatment.