The common cause of groin bumps with painful symptoms is swollen lymph nodes, which are commonly caused by infections of the soft tissues of the lower limbs, including phlebitis, especially thrombophlebitis, or in one case, superficial inguinal lymph node enlargement secondary to tinea pedis or simple soft tissue infections, cellulitis, and dengue, etc. The patient also has swelling, pain, and fever in the lower limbs. In this case, the affected limb should be elevated, and systematic anti-infective treatment should be applied, including penicillin or cephalosporin anti-inflammatory drugs, as well as wet application of magnesium sulfate to the wound surface, which will gradually improve the symptoms. There is also a case of lesions in the anal canal and rectum, especially malignant tumors that have metastasized to the inguinal lymph nodes. Patients may present with a localized mass that is fused and fixed, with significant pressure pain. In this case, a pathological biopsy may be performed to clarify the diagnosis.