It is not possible to stop taking rabeprazole after stenting. You need to take rabeprazole after stenting to prevent the occurrence of gastrointestinal bleeding, and you should not stop taking rabeprazole on your own, you need to follow your doctor’s instructions. Post-stenting usually refers to the aftermath of percutaneous coronary intervention (PCI), which is used to treat patients with acute coronary syndromes. Although the implantation of stent can recanalize the blocked coronary vessels, the stent itself is an ex vivo foreign body, which is prone to thrombus re-formation. In order to prevent re-infarction and other subsequent ischemic events, the combination of clopidogrel + aspirin is commonly used in the first year of the post-PCI period as the standard of care. Rabeprazole is not a mandatory drug after PCI, and it is not particularly useful for the treatment of primary disease. However, because the combination of clopidogrel and aspirin may lead to gastrointestinal bleeding, rabeprazole can inhibit the production of gastric acid, thus protecting the gastric mucosa and preventing bleeding, and the addition of rabeprazole after PCI can prevent gastrointestinal bleeding. In conclusion, after stenting → use of “clopidogrel + aspirin” to prevent reinfarction → easy to cause gastrointestinal bleeding → use of rabeprazole to prevent gastrointestinal bleeding. Even with the use of rabeprazole, there are still a few cases of gastrointestinal bleeding in the clinic. Gastrointestinal bleeding is potentially life-threatening, so do not discontinue rabeprazole on your own. Adverse effects of rabeprazole: granulocyte deficiency, dizziness, jaundice, allergic reactions, diarrhea, etc.. Contraindications: it is forbidden to use rabeprazole together with rilpivirine for allergic patients. If there are adverse reactions or contraindications to taking rabeprazole, the need to stop or change the drug, you need to change the treatment program under the guidance of the clinician.