What medication do I take for a tight head? If the head is tight and tense, there may be several reasons for that, according to the different causes of the decision is a different program: the first reason is probably due to tension headache, for tension headache to take the drug is tizanidine, and eat a drug called blood clearing brain particles. The second cause is chronic cerebral blood supply deficiency. For this phenomenon, you can take blood-supply and oxygen supply to the brain by taking blood-supply and oxygenation drugs such as blood-supply granules, blood clotting capsules, and Jinado tablets. The third reason may be caused by psychological factors, especially anxiety and depression, which can be treated by taking anti-anxiety and anti-depressant drugs.