The cause of vitiligo is not clear, and a variety of pathogenic factors, mainly including genetic factors, mental factors, immune factors. 1. genetic factors: clinical research shows that in the vitiligo patient’s family can appear more than one vitiligo patients phenomenon, predicting that the disease may have a certain heredity and family gathering. 2. mental factors: some patients in vitiligo before the history of mental trauma, so clinically deduced that the mental damage is one of the causes of vitiligo. 3. immune factors: may be due to the presence of patients in the body to attack the melanocyte immunoreactive substances, resulting in melanocyte dysfunction and lead to vitiligo. There may also be other reasons, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, give targeted treatment or treatment.