The mechanism of the ketogenic diet for epilepsy (sheep epilepsy) is still unknown, but the history of the ketogenic diet for epilepsy (sheep epilepsy) has a long history. The ketogenic diet simulates the metabolic process of a normal human body in a state of starvation, and was first developed in the 1920s by changing the proportion of food components in the diet to reduce seizures. However, the ketogenic diet was gradually abandoned with the introduction of early antiepileptic drugs because it was very tedious to prepare and did not provide much control of seizures. Since then, of course, new generations of anti-epileptic (sheep epilepsy) drugs have been used in the clinic, but still 20%-30% of seizures (sheep epilepsy) are difficult to control. Therefore, in recent years, the ketogenic diet as a special dietary therapy has received renewed attention and is used in the treatment of refractory epilepsy (sheep epilepsy). Currently, the ketogenic diet is widely used worldwide, and many retrospective and prospective clinical studies have concluded that the ketogenic diet responds well in the treatment of refractory epilepsy (sheep epilepsy). However, due to the lack of a global unified ketogenic diet treatment protocol, countries such as Europe and the United States are observed with their own formulated diet protocols, making it difficult to assess clinical data in general. Side effects cannot be ignored: The ketogenic diet may have adverse effects on the body, and the common early adverse effects are: dehydration; gastrointestinal disorders, of which diarrhea is the most common, followed by nausea, vomiting, and constipation; infectious diseases, mainly pneumonia, cystitis, and non-specific fever; other metabolic disorders, such as hypertriglyceridemia, hypercholesterolemia, hypolipoproteinemia, symptomatic hypoglycemia Other metabolic disorders such as hypertriglyceridemia, hypercholesterolemia, hypolipoproteinemia, hypomagnesemia, hyponatremia, persistent acidosis, and rarely, hepatitis and acute pancreatitis. Long-term adverse effects include reduced bone mineral density, kidney stones, iron deficiency anemia, and secondary carnitine deficiency. Therefore, before starting ketogenic diet therapy, liver function, kidney function, blood glucose, blood lipids and blood ions of the children should be tested; during the treatment, blood glucose, blood lipids and liver and kidney functions should be monitored regularly.