Leukoplakia is a disease in which the skin develops white spots due to lack of melanin as a result of destruction of melanocytes in the skin. The treatment is mainly based on medication and laser surgery. 1. Drug treatment: topical calcium-modulated phosphatase inhibitor is applicable to both adults and children, and this kind of drug can be used on the face, mucous membranes and other thin and tender parts of the face, and according to the age, it can be chosen to be applied with 0.03%, 0.1% tacrolimus ointment or 1% pimecrolimus cream. Topical topical corticosteroids may also be used. The medication should be used as prescribed by the doctor. 2. Laser surgery: you can also have aesthetic treatment in regular hospitals, pulsed laser therapy combined with fractional laser therapy, photodynamic therapy, 308 excimer laser therapy; if the area is relatively large, you can have surgery to improve the treatment with surface skin transplantation. It is suggested that patients with leukoplakia should go to the hospital in time and follow the doctor’s instructions for treatment.