Vaccination is not recommended for babies with Mycoplasma infection and can be delayed until the disease has resolved. Mycoplasma infection in babies is most likely to cause pneumonia in children, and at the same time, some clinical symptoms may occur, such as cough, fever, sore throat, headache and so on. At this time, vaccination may produce some adverse reactions, such as mild fever, general discomfort, mental disorientation, etc. These adverse reactions will be superimposed on the symptoms of mycoplasma infection, which will aggravate the baby’s discomfort. Therefore, when mycoplasma infection, it is recommended to first treat the baby’s primary disease, control mycoplasma infection, and then select the vaccination date after healing. Avoid aggravation of the disease or vaccine reaction.