Mycoplasma infection refers to a certain mycoplasma microorganism that enters the human body from the outside and then survives and reproduces in its body, which is contagious to a certain extent. Mycoplasma infections are often contagious, and the main modes of transmission are contact, droplet and sexual transmission. Mycoplasma can survive in the soil and beetles, animals and human body, when a person is in contact with the soil carrying mycoplasma or animals and other objects, may be infected; and mycoplasma in the human body mainly through the respiratory system, such as droplets to spread, sex will also be infected with mycoplasma infected by one party to the other party. Therefore, usually should do a good job of mycoplasma infection prevention, in contact with unclean soil, water or objects, should be timely washing hands and disinfection sterilization, in the period of pneumonia and other respiratory diseases are prevalent, less to go to the crowded places, and wear a good mask, in order to prevent droplet infection. When having sex, we should ensure the cleanliness and hygiene of private parts and take certain protective measures. If one of the spouses has mycoplasma infection, he or she should be treated in time and do a good job of preventing the infection when they are living together. If both parties are infected, they need to be treated at the same time, so as not to be infected again after one party is cured. Mycoplasma infections are contagious, and sexual and droplet transmission is more common, so attention should be paid to the prevention of infection in normal times.