Mycoplasma gynecologicum infection can easily lead to endometritis, vaginitis and pelvic inflammatory disease and other gynecological diseases, which need to be actively treated. Women with mycoplasma infections need to pay attention to, otherwise easy on the reproductive system health impact, the current use of a wider range of mycoplasma infections treatment for Western medicine, available drugs have three major categories, of which macrolides are the first choice of drugs, moxifloxacin and other fluoroquinolones also have a certain effect, can be done in the aetiological examination to determine the type of mycoplasma, and then according to the doctor’s guidance on the medication. At the same time, due to the special structure of the infected area, women also need to be assisted with certain topical antibacterial drugs, such as vaginal suppositories, etc., which can directly kill the chlamydia in the vaginal area. In addition, dietary control is also very important for the treatment of mycoplasma infection, patients should eat light and protein-rich food, can enhance their own immunity, resistance to mycoplasma, but also the use of traditional Chinese medicine to regulate, and strengthen the hygiene of the vulva care, it is best to husband and wife common treatment, so as to avoid re-infection due to conjugal life after the cure. The treatment of Mycoplasma gynecologicum infection is based on oral medication and supplemented with topical antimicrobials, while eating a reasonable diet and maintaining cleanliness and hygiene of the private parts are also helpful.