Fetal neural tube abnormalities are usually detectable. At 15-20 weeks of pregnancy, pregnant women can have blood drawn for Down’s syndrome screening. Down’s screening checks for the risk of neural tube malformations and trisomy 21, and if the neural tube malformation is a high risk, it is important to check for it at a subsequent 3D or 4D ultrasound. Ultrasound can confirm the diagnosis of fetal neural tube malformations such as anencephaly, spina bifida, and cerebrospinal bulge. Women need to take folic acid supplements in the first trimester of pregnancy before preparing for pregnancy, which can prevent the occurrence of neural tube malformations. At the same time, pregnant women should have regular maternity checkups during pregnancy, and don’t miss any of the tests that need to be performed. If any problems appear in the examination, you should seek medical treatment in time and deal with them under the guidance of the doctor.