Mammary adenocarcinoma of the sweat gland is a relatively serious cancer. Mammary gland adenocarcinoma is a malignant tumor mainly composed of sweat gland type cells of the mammary gland, also known as sweat gland-like carcinoma. It mainly develops in the upper outer quadrant, mostly in middle-aged women, and belongs to invasive special carcinoma, which is relatively rare in clinic. Breast sweat gland carcinoma should be treated as early as possible to prevent axillary lymph node metastasis and liver metastasis, etc. If there is no contraindication to surgery, breast-conserving surgery or radical mastectomy can be chosen according to one’s own condition. Besides surgical resection of the lesion, radiotherapy, chemotherapy, endocrine therapy and other comprehensive treatments are also available, which can help to improve the cure rate of the disease. Breast adenocarcinoma is more serious, it is recommended to go to the hospital in time to avoid delaying the condition.