Recently, the International Journal of Chronobiology published an important article, “The relationship between work and rest and morbidity and mortality in the UK Biosample”. Night owls who stay up at night and don’t get up in the morning, or have trouble getting up, are at higher risk of “early death” than those who go to bed early and get up early. The study, based on a sample of nearly 500,000 people in the British biobank, found that people who do not sleep at night and do not get up in the morning have a 10% higher risk of death than those who sleep early and get up early. In the study sample, 50,000 people in the 6.5-year sampling process faced a higher risk of death. Effects of staying up late on the body Staying up late for long periods of time can damage general health because, in the human body, both adrenocorticotropic hormone and growth hormone are secreted during nighttime sleep. The former is secreted before dawn and has the function of promoting the body’s sugar metabolism and safeguarding muscle development. 1, wrinkles increase According to the London School of Sleep report, a week, two hours less sleep per day can have a serious impact on appearance. The number of fine lines and wrinkles among the women who participated in the survey rose by 45%, and the number of spots rose by 13%. People’s eyes become red and puffy, the skin becomes loose and saggy, and more wrinkles grow. 2. Hair loss Alopecia areata is a kind of autoimmune non-scarring hair loss, commonly known as “ghost shaving”, in which the hair falls out unknowingly. It is mainly caused by emotional factors. Anxiety and shock may also cause baldness. Staying up all night may cause endocrine disruption, which can also cause baldness. 3. Sudden deafness Sudden deafness is when you can’t hear anything all of a sudden when you were fine. Frequent late nights, long-term fatigue, and lack of sleep can hinder the blood supply to the inner ear, which can easily lead to sudden deafness once it is stimulated by external factors (such as sudden temperature changes and viral infections). 4, vision loss Staying up late can do more harm to your eyes than simply having “panda eyes”. Long time overload eyes, will make the eyes appear pain, dryness and other problems, and even make people suffer from dry eye disease; long-term overwork caused by staying up late, may also induce central retinitis, resulting in a sudden drop in vision. 5, neurasthenia The next day after staying up late, the sympathetic nerve is difficult to fully excited, will make people no spirit, dizziness, memory loss, inattention, slow reaction, forgetfulness and dizziness, headache, etc.. Over time, there will be neurasthenia, insomnia and other more serious problems. 6, Alzheimer’s disease A recent study by scientists showed that when rats do not get enough sleep, it makes the brain show bad omens and may trigger Alzheimer’s disease (dementia). 7, hypertension, sudden death Research shows that chronic sleep deprivation is an important causative factor of hypertension, which also makes the late night people suffer from all kinds of sudden cardiovascular disease, the chances of a great increase in serious will lead to sudden death. 8, diabetes For people with a family history of diabetes, staying up late often increases the chances of developing diabetes. Compared to others, people with a family history of diabetes have certain triggers for the disease, and if the conditions are right, just like a seed meeting the right environment, it will soon take root and sprout. 9. Cancer Medical research shows that people who stay up late are more likely to develop cancer than those who sleep normally. Take pancreatic cancer as an example, the incidence rate of people who stay up late often is more than three times higher than the average person. Staying up late can affect the normal division of cells, which can lead to cell mutation and produce cancer cells. 10, immune disorders Staying up late for a long time will lead to dysfunction of the body’s immune function, which will be manifested in the kidneys to produce nephritis; in the skin may be lupus erythematosus; in the joints is rheumatoid arthritis …… body in a subhealthy state, flu and other respiratory diseases, gastroenteritis and other digestive tract diseases will come to the door.