There are several cases of white dots on lips: first, it may be sebaceous ectopic, white dots like pinhole, corn grain size and densely distributed, no obvious protrusion in the lip mucosa, no abnormal discomfort, more obvious when the skin is taut, this situation will not cause abnormalities, discomfort, no need for therapeutic intervention; second, it may be viral infection, herpes-like lesions on the lips, white dots like pinprick, raised feeling, looks like small transparent blisters, which can be accompanied by itching, pain, throat inflammation and other symptoms, and can also cause systemic symptoms, such as fever, and require antiviral treatment, such as the use of drugs such as acyclovir, ribavirin and interferon, applied topically or taken orally; third, it may be an ulcer on the lip, with a yellowish-white indentation of the lesion, surrounded by redness and swelling, accompanied by pain, which increases when eating; fourth, it may be a white spot of the oral mucosa or Flat moss-like mucous membrane type lesions, the lesions are white patches or white reticulation, stripes, with burning, numbness, roughness and other abnormalities, need to go to the hospital as soon as possible to confirm the diagnosis, the use of drugs for symptomatic treatment, to avoid aggravation of the disease, increasing the difficulty of treatment.