White spots and dark spots, with a higher possibility of malignant tendency. There are many reasons for skin spots, the main factors are genetic factors, such as freckles; there are also age spots and sun spots caused by lack of sunscreen; there are also some immune factors, such as systemic lupus erythematosus, etc. Skin cancer is the most malignant tumor of the skin. Skin cancer is the most common malignant tumor of the skin, in which the black spot or white spot may be more likely to appear skin cancer, white spot mainly appears on the back of the hand or perineum, black spot may be big or small, with variable shape, similar to nevus. However, if the plaque increases rapidly, it may be a symptom of some malignant tumors, such as primary liver cancer, skin cancer, malignant melanocytic carcinoma, basal cell carcinoma, squamous cell carcinoma and so on. If there are serious plaques, it is necessary to consult a doctor in time to find out the cause of the disease, and not to listen to advertisements freely.