Patient: Description of the condition (time of onset, main symptoms, hospital visited, etc.): Runny nose, nasal water flowing backwards, dry nose and nasal congestion when blowing on the air conditioner. On anterior rhinoscopy, the nasal mucosa was pale and edematous, and watery nasal discharge and a small amount of thin mucous nasal discharge were seen. Sinus CT was taken, and the sinuses were not inflamed. TIgE (total IgE) 248,47 Dust mite ++ Recurrent episodes Prof. Wang: The main symptoms of rhinitis: runny nose, backward flow of nasal water, dry nose when blowing air conditioner, nasal congestion. The nasal mucosa is pale and edematous on anterior rhinoscopy, with watery nasal discharge and a small amount of thin mucous nasal discharge. A sinus CT was taken and the sinuses were not inflamed. Whenever the symptoms are obvious, I use Rayocort+Equil+Xantamine, and the symptoms basically disappear in about 7 days, but once I stop the medicine for a few days, the symptoms come out again, I heard that these drugs are hormones, 1. How long can these three drugs be used? (I am very worried that long-term use may cause septal perforation) 2. Wang Chengshuo, Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital: The examination shows that it is consistent with allergic rhinitis caused by mite allergy. The combination of the three drugs is reasonable. Do not stop the medication immediately after the symptoms disappear, continue the medication for 1 week to make the symptoms stable. Also do a good job of anti-mite treatment, air conditioning outlet is an important source of mites. Another: Only Reynolds is a nasal spray hormone and has very little systemic absorption. All three drugs can be used for a long time. The three drugs can be used in combination for two weeks, and then spray Raynaud’s alone can be. The total course of treatment generally does not exceed 3 months. Patient: Thank you for your answer. 1. Is it normal to have a certain irritating sensation of slight pain in the nasal cavity when spraying Echolux? (I don’t feel this sensation when I spray Rayocort) 2. Can I achieve the desensitization effect after using Rayocort nasal spray hormone for 3 months? 3.What is the difference between Reynocort and Nesuna? Wang Chengshuo, Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital: 1. Maybe the reaction of the mucous membrane to the drug is related, there is no need to worry about it. The purpose of long-term use is to steadily control nasal inflammation and reduce the threshold of mucosal reoccurrence of symptoms. And desensitization treatment is completely different. 3, both are nasal spray hormone, pharmacological indicators have their own advantages and disadvantages, do not need to entangle. The latter is more suitable for children. Patient: Professor Wang: Hello, can dexamethasone eye drops help with allergic rhinitis? Wang Chengshuo, Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital: Dexamethasone is one of the first hormones used clinically, with a long half-life and a long retention time in the body. The biggest disadvantage is that the systemic absorption rate of local nasal drops is very high, so the chance of causing systemic side effects will be high. On the other hand, nasal spray hormones such as Reynocort, Cozultan or Endosulfan are specially used for local dosage, which are rarely absorbed systemically and are safe even for long-term use. Therefore, there are specialties in the field and they should not be mixed up.