The three swords to deal with allergic rhinitis

  Allergic rhinitis should top the list of all types of rhinitis, with a large number of people suffering from the disease and the difficulty of treating it, leaving other types of rhinitis in the dust. In fact, as early as the mid-20th century, the principles of allergic rhinitis treatment have been basically established, but why do people feel that this disease can not be cured? This article will talk about the three swords of allergic rhinitis treatment.  Allergic disease is a systemic disease that can occur in multiple locations. The more common ones are nose, airways and lungs, and skin. Medical advances have not yet developed a drug that can achieve short-term use and permanent eradication. Whether in the nasal cavity or trachea or skin, treatment should be comprehensive, and there are three main swords to deal with allergic rhinitis: The first sword: find and avoid allergens Allergens need to be examined professionally including skin prick, patch test, blood antibody test and so on, not by guesswork. If the allergen is identified and removed from contact, the symptoms of allergic rhinitis will be greatly reduced or even eliminated. In some cases where detailed allergen testing has not revealed a specific allergen, it is important to consider whether it is vasomotor rhinitis or eosinophilia, both of which have almost identical symptoms to allergic rhinitis but are not allergen related.  The presence of allergens is the source of all allergic diseases. Foreign studies often consider pollen and grass as the main culprits of allergic rhinitis, but in fact, the types of allergens vary from place to place. For example, grass is only found in northern China, while Japan, Korea, Europe and the United States have not found this allergen; one of the 100 most influential domestic academic papers in China in 2010: “Analysis of Inhalation Allergen Spectrum in Patients with Allergic Rhinitis in Beijing”, in which it is proposed that dust mites are the first culprit of allergic rhinitis in Beijing, accounting for a much larger proportion than pollen and grass. And dust mites can exist in any area, especially in our residence, and complete removal from contact is almost impossible. Therefore, causing many allergic rhinitis recurring and relocating.  The first sword is easier said than done, as various inhalant allergens are pervasive, and most of them have to be replaced by another place to live if we want to get rid of them completely. It is difficult for ordinary people to do, which requires the second sword: the treatment of allergy drugs.  Allergic rhinitis drugs are also divided into several categories, there are antihistamines such as the new generation of diclazuridine, levocetirizine, fexofenadine, in recent years there are also antihistamine nasal sprays appear; leukotriene receptor antagonists, montelukast. Glucocorticosteroid nasal spray such as budesonide, fotetaxone propionate, mometasone furoate nasal spray, nasal spray hormone almost all the effects are concentrated in the nasal cavity, systemic absorption is very little, to become the first choice of drugs for the treatment of moderate and severe allergic rhinitis, but for the “hormone” secondary inexplicable fear, so that such drugs are far from the national The second sword is the most widely used, but the most widely used. This second sword is the most widely used, but the drawback is also obvious.  The last sword: specific allergen immunotherapy (commonly known as desensitization therapy) The second sword can only control allergy symptoms but cannot eradicate them. Especially in children, allergic rhinitis can be controlled by desensitization therapy to reduce the risk of developing asthma in adulthood. However, the disadvantage of immunotherapy is that the treatment period is long, and injectable desensitization usually takes more than two years. There is a risk of provoking a severe allergic reaction during treatment. Early immunotherapy is done by injection and can be really difficult to adhere to. There are already oral immunotherapy drugs for dust mites – dust mite drops – in clinical use, and it is hoped that more types of oral immunotherapy drugs will be developed in the future.  Allergic rhinitis is not a terminal disease, but the cost of the “first sword” and “third sword” to cure it is relatively high, and foreign patients can only look at the “sword” by changing their living area or city of residence for the majority of people in China. “sigh”; “desensitization” because the course of treatment is too long, it is difficult to adhere to. The second sword, however, is feasible for most allergic rhinitis patients through the “training and conditioning” of regular doctors. Compared to more “terminal” diseases, allergic rhinitis, in fact, has been very gentle, just did not play the “three swords”.