Toothache causing headache on half of the face may be pulpitis, periodontal abscess, wisdom tooth pericoronitis, etc., which need to be treated with root canal therapy, periodontal sequential therapy, and removal of the wisdom tooth causing toothache. 1. Pulpitis: It mainly manifests as pain from hot and cold stimulation, and the pain continues after the stimulation is removed. In acute attacks, there may be obvious involving pain, resulting in half of the face pain, and can not be localized. It needs to be examined to clarify the tooth position and root canal treatment to remove the infected pulp and dentin wall before filling treatment. 2. Periodontal abscess: mainly manifested as swelling and throbbing pain of the tooth, which can lead to swelling and pain on half of the face. Anti-inflammatory treatment is carried out in the acute stage, and periodontal sequence treatment (supragingival scaling, subgingival scraping, flap surgery and other operations) is carried out after the symptoms are relieved, and if the result is unsatisfactory, extraction is carried out if necessary. 3. Wisdom tooth pericoronitis: the main manifestation of mild swelling and pain, severe cases can appear restricted opening, swallowing pain, facial swelling, half of the face are painful. It is recommended to carry out blind bag rinsing, oral cephalosporin antibiotics and nitroimidazole antibiotics, such as cefuroxime, metronidazole, etc., to be symptomatic relief after the removal of wisdom teeth. It is recommended to go to the stomatology department of the regular hospital, to be examined by the physician to clarify the diagnosis, and to treat the cause. Under the guidance of the physician to use drugs.