Treatment for right-sided pyriformis syndrome includes medications, injections, physical therapy, and surgery. Pharmacologic treatments for pyriformis syndrome include oral nonsteroidal anti-inflammatory drugs such as celecoxib, muscle relaxants such as etoperisone, and nutrient neurologic drugs such as methylcobalamin. Pyriformis injection therapy with a combination of hormones and local anesthetics can be effective in improving pain in pyriformis syndrome. Tui na, massage, and manual release can also provide varying degrees of relief from the symptoms caused by pyriformis syndrome. Surgery can be performed if conservative treatment fails to improve symptoms. During surgery, the tendons of the pyriformis muscle are cut and the sciatic nerve is decompressed. Patients with right sided pyriformis syndrome are advised to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.